Tissue cytology of masses on my dog
Posted: Wed Apr 04, 2018 10:31 am
I took these samples from my dog last night. They are from two different masses that have been growing over the course of several weeks. Currently, I'm consulting with veterinary oncologists for a preliminary diagnosis. I'm confidant that the first mass is a lipoma. My guess for the second mass is perianal adenoma/ adenocarcinoma. In the second mass, I can identify several cytologic characteristics of malignancy (ex., cellular and nuclear pleomorphism, basophilia, anisokaryosis, and variable nucleolar size, shape, and number); however, no evidence of multinucleation, increased or abnormal mitosis, abnormal chromatin patterns, or phagocytic activity). I'm currently planning to having both masses removed, so I'll try to provide updates as to the definitive diagnoses and images of tissue histopathology (if I can get my hands on the slides).
[Note: Tissue cytology occasionally leads to a preliminary diagnosis upon which diagnostic/ therapeutic decisions can be made. Biopsy/ surgical resection and tissue histopathology is usually required to make a definitive diagnosis and to determine if adequate surgical margins were obtained.]
Fine Needle Aspirate of Mass 1 (possible lipoma): https://flic.kr/s/aHskyN9bQS
Fine Needle Aspirate of Mass 2 (guess of perianal adenoma/ adenocarcinoma): https://flic.kr/s/aHsmh4xBj3
[Note: Tissue cytology occasionally leads to a preliminary diagnosis upon which diagnostic/ therapeutic decisions can be made. Biopsy/ surgical resection and tissue histopathology is usually required to make a definitive diagnosis and to determine if adequate surgical margins were obtained.]
Fine Needle Aspirate of Mass 1 (possible lipoma): https://flic.kr/s/aHskyN9bQS
Fine Needle Aspirate of Mass 2 (guess of perianal adenoma/ adenocarcinoma): https://flic.kr/s/aHsmh4xBj3