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Transforming conventional fluorescence microscopy images to super-resolution using Machine Learning models

Posted: Fri Dec 24, 2021 5:56 am
by vadimzinchuk
Dear All,

We have created a set of Machine Learning 🧠 🤖 models to transform conventional fluorescence microscopy images to super-resolution. The set consists of 3 models: denoising, axial resolution restoration, and super-resolution reconstruction. It achieves the high-quality transformation of conventional fluorescence microscopy images to images comparable with super-resolution while preserving and enhancing image details.

Our results are presented as a pre-print on Nature Protocol Exchange. Please read more and share your comments: https://protocolexchange.researchsquare ... ex-1721/v1

We will gladly explain how to apply these models in your studies, just ask.

Best wishes,

Vadim Zinchuk & Olga Grossenbacher-Zinchuk

Re: Transforming conventional fluorescence microscopy images to super-resolution using Machine Learning models

Posted: Fri Dec 24, 2021 8:33 am
by MichaelG.
.

Thank you for sharing that … I have downloaded the PDF

Other readers may find it helpful to watch the video of a recent Zoom presentation by Dr Susan Cox
which is now available on the Royal Microscopical Society’s YouTube channel:
https://youtu.be/rl3MFhPjBHQ

MichaelG.

.
Ref. https://www.kcl.ac.uk/lsm/research/divi ... x/coxsusan

Re: Transforming conventional fluorescence microscopy images to super-resolution using Machine Learning models

Posted: Fri Dec 24, 2021 8:41 am
by vadimzinchuk
You are very welcome. Feel free to comment either on the Nature Protocol Exchange site or here. We plan to update the protocol based on users' feedback.

Re: Transforming conventional fluorescence microscopy images to super-resolution using Machine Learning models

Posted: Fri Dec 24, 2021 9:42 pm
by MichaelG.
I have downloaded the iPad App, but regrettably am not personally in a position to make use of it.
… I will, however, read the user manual with great interest; if only for my education:
https://www.geo.itunes.apple.com/book/c ... 2440?mt=11

MichaelG.

Re: Transforming conventional fluorescence microscopy images to super-resolution using Machine Learning models

Posted: Fri Dec 24, 2021 11:49 pm
by vadimzinchuk
Very good! Feel free to ask if you have any questions. To learn more about using Machine Learning models for the transformation of microscopy images, check our recent review: https://currentprotocols.onlinelibrary. ... 2/cpcb.101

Vadim