Is there a doctor in the house?

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neal Shields
Posts: 58
Joined: Sat Jun 04, 2022 8:02 pm

Is there a doctor in the house?

#1 Post by neal Shields » Sun Aug 14, 2022 9:37 pm

About 10 years ago, I purchased a lot of slides from a University Biology professor's estate. Included were a set of blood smears that were numbered with no descriptions. They had the name of a US Air Force Hospital that, as near as I can tell, closed shortly after the Viet Nam war. I suspect the slides were from the mid 1960s.

I also suspect they were study aids for new doctors who would use them to identify diseases.

At first I suspected tropical diseases such as Malaria. I think I have ruled that out.

I now think they are different types of Leukemia as most of them (except one) seem to have way above normal White Blood cell counts. One seems to have 90% Eosinophils. Another seems to have no white cells at all and the red cells it has look like they have been run through a wood chipper.

I have almost studied enough for a medical degree trying to figure out what I am looking at.

If anyone can shed any light I would find it very interesting.

https://www.flickr.com/photos/196001110 ... ed-public/

https://www.flickr.com/photos/196001110 ... ed-public/

https://www.flickr.com/photos/196001110 ... ed-public/

https://www.flickr.com/photos/196001110 ... ed-public/

https://www.flickr.com/photos/196001110 ... ed-public/

https://www.flickr.com/photos/196001110 ... ed-public/

https://www.flickr.com/photos/196001110 ... ed-public/

https://www.flickr.com/photos/196001110 ... ed-public/

Thanks

neal Shields
Posts: 58
Joined: Sat Jun 04, 2022 8:02 pm

Re: Is there a doctor in the house?

#2 Post by neal Shields » Tue Aug 16, 2022 7:15 pm

I got my 100x objective out. These are better.

https://www.flickr.com/photos/196001110 ... ed-public/

https://www.flickr.com/photos/196001110 ... ed-public/

https://www.flickr.com/photos/196001110 ... ed-public/

I can't find anything on the internet that looks anything like the first picture.

Any suggestions appreciated
Neal

P.S. I hate cleaning up after oil

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imkap
Posts: 750
Joined: Thu Nov 25, 2021 9:44 pm

Re: Is there a doctor in the house?

#3 Post by imkap » Tue Aug 16, 2022 7:30 pm

neal Shields wrote:
Tue Aug 16, 2022 7:15 pm

P.S. I hate cleaning up after oil

Me too :D, but I can't help you... I'll ask my cousin

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imkap
Posts: 750
Joined: Thu Nov 25, 2021 9:44 pm

Re: Is there a doctor in the house?

#4 Post by imkap » Tue Aug 16, 2022 7:40 pm

He said he doesn't know, but has an immunology exam in a month, so he might know by then :lol: or he'll ask his professor if he has a chance... Not much help from me :D

PeteM
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Location: N. California

Re: Is there a doctor in the house?

#5 Post by PeteM » Tue Aug 16, 2022 10:29 pm


MicroMan2
Posts: 158
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Location: Canada,Alberta

Re: Is there a doctor in the house?

#6 Post by MicroMan2 » Tue Aug 16, 2022 11:49 pm

The second 100x photomicrograph that features a cell almost like an Eosinophil is actually a Neutrophil. That particular slide seems to be a case of Chediak-Higashi. This immunodeficiency impedes the granulation of Neuts preventing adequate respiratory burst used to kill pathogens, mainly bacteria.

MicroMan2
Posts: 158
Joined: Tue Oct 14, 2014 4:20 pm
Location: Canada,Alberta

Re: Is there a doctor in the house?

#7 Post by MicroMan2 » Tue Aug 16, 2022 11:57 pm

Apologies the granulation is way too fine to be called Chediak Higashi.

charlie g
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Joined: Mon Oct 20, 2014 7:54 pm

Re: Is there a doctor in the house?

#8 Post by charlie g » Wed Aug 17, 2022 12:21 pm

Hi, neal and all...I simply 'googled' : "images for blood smears"..please try this as your specimens show up in the first images...and with labels.'' hope you try this.

BTW, neal, I'm impressed with how clear your 100X images are..I am having trouble with lint/ dust on either my relay lens, objectives, or both....aahhh , charlie g

neal Shields
Posts: 58
Joined: Sat Jun 04, 2022 8:02 pm

Re: Is there a doctor in the house?

#9 Post by neal Shields » Sat Aug 20, 2022 1:38 am

Found it!

After a week of internet searching i stumbled on a Youtube video this evening.

Pyknotic neutrophils.

Thanks for all the help

Neal

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